USA TODAY: After a decade, CRISPR gene editing is a 'revolution in progress.' What does the future hold?

Medical innovations typically take 17 years from the time a lightbulb goes off in a scientist's head until the first person benefits. But every once in a while, an idea is so powerful and so profound its effects are felt much faster.

Five Blood Transfusions, One Bone Marrow Transplant — All Before Birth

SAN FRANCISCO — In the three months before she was even born, Elianna Constantino received five blood transfusions and a bone-marrow transplant. All were given with a needle passed through her mother’s abdomen and uterus, into the vein in her umbilical cord.

UCSF News: Infant Gene Therapy is a Breakthrough for Artemis-SCID Patients

Ten young children born without functioning immune systems and lacking the ability to fight infections are on track for healthier lives thanks to a new gene therapy treatment pioneered at UC San Francisco, reports a Dec. 22 study in the New England Journal of Medicine.

NYT Opinion: We Can Cure Disease by Editing a Person’s DNA. Why Aren’t We?

The parents of a 2-year-old girl write that their daughter “could die within the next year” because a genetic mutation is causing her heart to fail. “Time is quickly running out for me,” writes a man in his mid-30s whose DNA harbors a genetic mistake certain to destroy his brain within a matter of...

UCSF News: Accelerating Transformational Research into Cell Transplantation for Patients with Type 1 Diabetes

A personal investigation into the lifelong implications of his type 1 diabetes (T1D) culminated in a $7 million gift from Mike Gordon, co-founder of Meritech Capital Partners, and his wife, Loren, to help UCSF surmount a key impediment to treating the disease. The funds will support world-class...

UCSF News: Sickle Cell Clinical Trial Aims to Cure Disease by Correcting Patient’s Mutated Gene

UCSF Benioff Children’s Hospital Oakland has received the largest research trial grant in its history to launch an innovative clinical trial that aims to cure sickle cell disease. The study, which plans to enroll its first patient later this year, will use CRISPR-Cas9 gene-editing technology on...

UCSF News: Living Therapeutics Initiative Will Accelerate Development and Delivery of Revolutionary Treatments

UC San Francisco is launching a new initiative to propel the development of living therapeutics – a category of treatments broadly defined as human and microbial living cells that are selected, modified, or engineered to treat or cure disease – and bring them quickly to patients. 

CIRM: Regulated, reliable, and reputable: Protect patients with uniform standards for stem cell treatments

ABSTRACT - treatments are emerging amidst reports of patients being injured by unproven “stem cell” interventions. At this juncture, it is vital to be supporting the continued development of promising regenerative medicine products while protecting patients from the risks posed by unproven...

Gene Therapy For Inherited Blood Disorder Reduced Transfusions

Gene therapy is showing promise for treating one of the most common genetic disorders. Results of a study published Wednesday show that 15 of 22 patients with beta-thalassemia who got gene therapy were able to stop or sharply reduce the regular blood transfusions they had needed to alleviate their...

UCSF Benioff Children’s Hospitals in Oakland and San Francisco To Begin Cutting Edge Stem-Cell Trials at CIRM-Funded Alpha Stem Cell Clinics

California Institute of Regenerative Medicine Awards Nearly $8 Million to UCSF for the Clinics